Vitamin E


Vitamin E is a fat-soluble vitamin that is required for the proper function of many organs, enzymatic activities and neurological processes.

May 7, 2019

Vitamin E is a fat-soluble vitamin that is required for the proper function of many organs, enzymatic activities and neurological processes. It plays the role of antioxidant, preventing free radical damage to specific fats in the body that are critical for your health and naturally slowing aging.
Consuming more vitamin E-rich foods can help treating and preventing diseases of the heart and blood vessels, such as chest pains, high blood pressure, and blocked or hardened arteries. It is found only in plant foods, including certain oils, nuts, grains, fruits and wheat germ. It is also available as a supplement.
Vitamin E is used for treating vitamin E deficiency, which is rare. However, the deficiency can occur in people with certain genetic disorders and in very low-weight premature infants.

Dietary Sources:

Getting enough vitamin E seems to be especially critical for the infants, the elderly, and women who are or may become pregnant.
Foods that are rich in Vitamin E are:

  • Sunflower Seeds: 1 cup — 33.41 milligrams (220 percent)
  • Almonds: 1 cup — 32.98 milligrams (218 percent)
  • Hazelnuts: 1 cup — 20.29 milligrams (133 percent)
  • Wheat Germ: 1 cup plain, uncooked — 18 milligrams (120 percent)
  • Mango: 1 whole raw — 3.02 milligrams (20 percent)
  • Avocado: One whole raw — 2.68 milligrams (18 percent)
  • Butternut Squash: 1 cup cooked and cubed squash — 2.64 milligrams (17 percent)
  • Broccoli: 1 cup cooked — 2.4 milligrams (12 percent)
  • Spinach: 1/2 cup cooked or about 2 cups uncooked — 1.9 milligrams (10 percent)
  • Kiwi: 1 medium — 1.1 milligrams (6 percent)
  • Tomato: 1 raw — 0.7 milligram (4 percent)

Vitamin E Deficiency:

Vitamin E deficiency is very rare as most of the people can get enough of this vitamin from their diet. It can occur due to malfunctions in terms of how nutrients are absorbed.
Vitamin E deficiency might occur in premature infant who is born weighing less than 3.5 pounds. But a pediatrician who specializes in the care of newborns will typically evaluate the nutritional needs of an infant to help spot and treat this early. People with fat absorption problems, which is a common problem for those who struggle with inflammatory bowel disease, may also struggle with a vitamin E deficiency in some cases.
As fat is needed for the absorption of the vitamin, people who have an issue with their dietary fat levels are at an increased risk. This includes anyone who has been diagnosed with cystic fibrosis, has had gastric bypass surgery, or people with malabsorption problems, such as Crohn's disease, liver disease or pancreatic insufficiency. Deficiency symptoms include loss of muscle coordination and impaired vision and speech.

Uses & Effectiveness:

Effective for:

Ataxia:

It is a movement disorder associated with vitamin E deficiency. The genetic movement disorder called ataxia causes severe vitamin E deficiency. Vitamin E supplements are used as part of the treatment for ataxia.

Vitamin E deficiency:

Taking vitamin E by mouth is effective for preventing and treating vitamin E deficiency.

Possibly Effective for:

Beta-thalassemia:

Taking vitamin E by mouth seems to benefit children with the blood disorder called beta-thalessemia and vitamin E deficiency.

Bladder cancer:

Taking 200 IU of vitamin E by mouth for more than 10 years seems to help prevent death from bladder cancer.

Leakage of chemotherapy drug into surrounding tissue:

Applying vitamin E to the skin together with dimethylsulfoxide (DMSO) seems to be effective for treating leakage of chemotherapy into surrounding tissues.

Chemotherapy-related nerve damage:

Taking vitamin E (alpha-tocopherol) before and after treatment with cisplatin chemotherapy might reduce the risk of nerve damage.

Alzheimer's disease:

Vitamin E might slow down the worsening of memory loss in people with moderately severe Alzheimer's disease. Vitamin E might also delay the loss of independence and the need for caregiver assistance in people with mild-to-moderate Alzheimer's disease. However, vitamin E does not seem to prevent the progress of the disease from mild to severe.

Anemia:

Taking vitamin E improves the response to the drug erythropoietin, which affects red blood cell production, in adults and children on hemodialysis.

Dementia:

People who consume vitamin E and vitamin C have a decreased risk of developing several forms dementia. However, it does not appear to reduce the risk for Alzheimer's dementia.

Dysmenorrhea:

Taking vitamin E for 2 days before and for 3 days after bleeding begins seems to decrease pain severity and duration during painful menstruation. It also help reduce menstrual blood loss.

Huntington's disease:

Natural vitamin E (RRR-alpha-tocopherol) can improve symptoms in people with early Huntington's disease. However, it does not seem to help people with more advanced disease.

Male infertility:

Taking vitamin E by mouth improves pregnancy rates for men with fertility problems. Taking high doses of vitamin E together with vitamin C does not seem to provide the same benefits.

Bleeding within the skull:

Taking vitamin E by mouth seems to be effective for treating bleeding in the skull in premature infants.

Bleeding within the ventricular system of the brain:

Taking vitamin E by mouth seems to be effective for treating bleeding within the ventricular system of the brain in premature infants.

Nitrate tolerance:

There is some evidence that taking vitamin E daily can help prevent nitrate tolerance.

Liver disease called nonalcoholic steatohepatitis:

Taking vitamin E daily seems to improve symptoms of NASH in adults and children.

Parkinson's disease:

Intake of vitamin E in the diet might be linked with a decreased risk of Parkinson's disease. However, taking all-rac-alpha-tocopherol (synthetic vitamin E) does not seem to have any benefit for people with Parkinson's disease.

Laser eye surgery or Photoreactive keratectomy:

Taking high doses of vitamin A along with vitamin E (alpha-tocopheryl nicotinate) daily seems to improve healing and vision in people undergoing laser eye surgery.

Premenstrual syndrome (PMS):

Taking vitamin E by mouth seems to reduce anxiety, craving, and depression in some women with PMS.

Physical performance:

Increasing vitamin E intake in the diet is linked with improved physical performance and muscle strength in older people.

Rheumatoid arthritis (RA):

Vitamin E taken along with standard treatment is better than standard treatment alone for reducing pain in people with RA. However, this combination does not reduce swelling.

Dyspraxia:

It is a movement and coordination disorder. Taking vitamin E by mouth together with evening primrose oil, thyme oil, and fish oils seems to improve movement disorders in children with dyspraxia.

Glomerulosclerosis:

It is a kidney problems in children. Taking vitamin E by mouth might improve kidney function in children with glomerulosclerosis.

An inherited disorder called G6PD deficiency:

Taking vitamin E by mouth, alone or together with selenium, might benefit people with an inherited disorder called G6PD deficiency.

Granuloma Annulare:

It is a type of skin sore. Applying vitamin E to the skin seems to clear up skin sores called granuloma annulare.

Sunburn:

Taking high doses of vitamin E (RRR-alpha-tocopherol) by mouth together with vitamin C protects against skin inflammation after exposure to UV radiation. However, vitamin E alone does not provide the same benefit. Applying vitamin E to the skin, together with vitamin C and melatonin, provides some protection when used before UV exposure.

Tardive dyskinesia:

It is a movement disorder. Taking vitamin E by mouth seems to improve symptoms associated with the movement disorder called tardive dyskinesia. However, it does not improve symptoms, but may prevent symptoms from worsening.

Fibrosis caused by radiation:

Taking vitamin E by mouth with the drug pentoxifylline seems to treat fibrosis caused by radiation. However, taking vitamin E alone does not seem to be effective.

Retinopathy of prematurity:

It is an eye disease in newborns. Taking vitamin E by mouth seems to be effective for treating an eye disease cause retinopathy of prematurity in newborns.

Uveitis:

It is swelling in the middle layer of the eye. Taking vitamin E with vitamin C by mouth seems to improve vision, but does not reduce swelling, in people with uveitis.

Possibly Ineffective for:

Age-related vision loss (age-related macular degeneration):

Taking vitamin E, alone or along with other antioxidants, is not effective for preventing or treating age-related vision loss.

Lou Gherig's disease (ALS):

It is a neurodegenerative disease. Taking vitamin E (alpha-tocopherol) along with conventional medication does not affect function or increase survival rates compared to conventional medication alone in people with Lou Gherig's disease.

Angina or Chest pain :

Taking vitamin E by mouth might have some effect on the functioning of blood vessels, but does not appear to reduce chest pain.

Atherosclerosis:

Taking vitamin E (RRR-alpha-tocopherol) by mouth does not appear to prevent the progression of atherosclerosis or hardening of the arteries. However, taking vitamin E and vitamin C might help prevent the progression of atherosclerosis in men.

Eczema:

Taking vitamin E, alone or along with selenium, does not improve symptoms of eczema. Red and itchy skin does not seem to improve.

Hot flashes related to breast cancer:

Taking vitamin E by mouth does not seem to reduce hot flashes in women who have had breast cancer.

Bronchopulmonary dysplasia:

It is a lung condition in infants. Taking vitamin E by mouth does not benefit newborn infants with a lung condition called bronchopulmonary dysplasia.

Cancer:

Taking a combination of vitamin E, vitamin C, beta carotene, selenium, and zinc does not seem to lower overall cancer risk. However, it might reduce the risk of cancer in men.

Colorectal cancer:

Taking vitamin E does not prevent the occurrence of colorectal cancer or the development of non-cancerous colorectal tumors, which are considered precursors to colon cancer.

Pharyngeal cancer:

People with diabetes who take vitamin E (RRR-alpha-tocopherol) by mouth do not have a reduce risk of developing mouth or pharyngeal cancer.

Prostate cancer:

Taking vitamin E supplements does not reduce the risk of developing prostate cancer, and might actually increase the risk.

Head and neck cancer:

Taking vitamin E (all-rac-alpha-tocopherol) daily during radiation therapy and for 3 years after the end of therapy does not seem to reduce the risk of head and neck cancer recurrence. There is some concern that taking vitamin E might actually increase the risk of tumor recurrence. People with head and neck cancer should avoid daily vitamin E supplements in doses over 400 IU daily.

Pancreatic cancer:

Taking vitamin E, alone or together with other antioxidants such as beta-carotene and vitamin C, does not seem to reduce the risk of developing pancreatic cancer.

High blood pressure:

Taking vitamin E by mouth does not seem to lower blood pressure in people already taking blood pressure medications.

Heart failure:

Taking vitamin E by mouth for 12 weeks does not seem to improve heart function in people with heart failure.

Duchenne muscular dystrophy:

Taking vitamin E with the drug penicillamine does not slow the progression of the muscle disease called Duchene muscular dystrophy.

Hemolytic anemia:

Giving vitamin E to premature infants does not have a beneficial effect on the abnormal breakdown of red blood cells known as Hemolytic anemia.

Liver disease:

Taking vitamin E does not reduce the risk of death in people with liver disease.

Myotonic dystrophy:

Taking vitamin E and selenium by mouth does not slow the progression of an inherited muscle disorder called myotonic dystrophy.

Mouth sores or oral musosal lesions:

Taking vitamin E (all-rac-alpha-tocopherol) for up to 7 years does not reduce the risk for mouth sores in men who smoke.

Osteoarthritis:

Taking vitamin E does not seem to decrease pain or stiffness in people with osteoarthritis. Vitamin E also does not seem to prevent the condition from becoming worse.

Pre-eclampsia:

Taking a combination of vitamins E and C does not reduce the risk of high blood pressure during pregnancy. However, taking a combination of vitamins E and C daily reduces the risk of high blood pressure in high risk women when started in weeks 16 to 22 of pregnancy.

Respiratory tract infections:

Taking vitamin E by mouth, alone or as a multivitamin, does not appear to decrease the risk of respiratory tract infections or the severity of symptoms once an infection develops.

Retinitis pigmentosa:

Taking vitamin E (all-rac-alpha-tocopherol) by mouth does not appear to slow vision loss, and might actually increase vision loss, in people with a condition called retinitis pigmentosa.

Scarring:

Applying vitamin E to the skin does not reduce scarring after surgery.

Likely Ineffective for:

Heart disease:

Taking vitamin E supplements does not prevent heart disease. However, increasing vitamin E intake in the diet might be beneficial.

Stroke caused by a clot or Ischemic stroke:

All-rac-alpha-tocopherol (synthetic vitamin E) might help prevent stroke in male smokers who have high blood pressure and diabetes. However, it might not reduce the risk of stroke.

Benign breast disease:

Taking vitamin E supplements does not seem to be effective for treating benign breast disease.

Breast cancer:

Although having higher blood levels of vitamin E might be linked with a reduced risk of breast cancer, increasing vitamin E intake from the diet or supplements does not reduce the risk of developing breast cancer.

Lung cancer:

Taking all-rac-alpha-tocopherol (synthetic vitamin E) for up to 8 years does not reduce the risk of developing lung cancer in men who smoke. Also, taking vitamin E (alpha-tocopherol) for up to 10 years does not prevent lung cancer or reduce the risk of death from lung cancer.

Death from any cause:

Taking vitamin E daily or every other day for up to 10 years does not reduce the risk of death from any cause. Also, regularly taking high doses of vitamin E might increase the risk of death.

Insufficient Evidence for:

Asthma:

Consuming more vitamin E in the diet seems to prevent asthma. However, taking vitamin E supplements does not have the same benefit.

Diabetes:

Vitamin E might be beneficial for people with diabetes. Vitamin E improves blood sugar control. Also, higher vitamin E intake in the diet is linked to a reduced risk of diabetes.

High cholesterol:

Taking vitamin E with vitamin C might benefit children with high cholesterol.

Cataract:

Taking vitamin E, alone or together with other vitamins or antioxidants, does not prevent the development or progression of cataracts. However, vitamin E might help reduce the risk of developing cataracts.

Infections related to chemotherapy:

Higher intake of vitamin E in the diet might reduce the risk of infection in children undergoing chemotherapy.

Stomach cancer:

Taking vitamin E plus beta-carotene or vitamin C and beta-carotene does not seem to prevent stomach cancer. However, consuming more vitamin E from the diet might slow the progression of stomach cancer.

IgA nephropathy:

Taking vitamin E can improve kidney function in children with a kidney disease called IgA nephropathy.

Intermittent claudication:

Difficulty walking due to poor blood flow in the legs occurs due to this disease. Taking all-rac-alpha-tocopherol (synthetic vitamin E) alone or together with beta-carotene by mouth does not appear to improve poor blood flow in the legs. However, taking vitamin E daily for 18 months reduces symptoms of intermittent claudication.

Ischemic reperfusion injury:

Taking vitamin E by mouth with vitamin C and conventional medication two days before bypass surgery and one day after surgery appears to reduce complications such as tissue damage after a blood clot. However, vitamin E does not appear to be beneficial when taken alone.

Liver transplant:

Taking vitamin E (tocopheryl succinate polyethylene glycol) might reduce the dose of immunosuppressant needed after a liver transplant.

Melanoma:

Taking vitamin E (RR-alpha-tocopherol) daily does not reduce the risk of developing skin cancer or Melanoma.

Nighttime leg cramps:

Vitamin E might reduce nighttime leg cramps.

Sickle cell disease:

Taking vitamin E with aged garlic extract and vitamin C might be useful for sickle cell anemia.
More evidence is needed to rate vitamin E for the uses in below condition.

  •     Skin disorders.
  •     Allergies.
  •     Chronic fatigue syndrome (CFS).
  •     Epilepsy.
  •     Common cold.
  •     Other conditions.